CST, 3207S, AMACR (2A10) Mouse Monoclonal Antibody

Monoclonal Antibody for studying AMACR. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, AMACR (2A10) Mouse Monoclonal Antibody (CST #3207) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity AMACR (2A10) Mouse Monoclonal Antibody detects endogenous levels of total AMACR protein. Species Reactivity: Human, Mouse Source / Purification Monoclonal antibody is produced by immunizing animals with a purified truncated recombinant human AMACR-His fusion protein. Background α-Methylacyl-CoA racemase (AMACR), an enzyme localized in peroxisomes and mitochondria, is involved in the β-oxidation of branched-chain fatty acids and fatty acid derivatives (1). AMACR has been reported to be a biomarker for prostate cancer (2-4). AMACR expression is also related to other types of cancers, such as hepatocellular carcinoma (1), noninvasive bladder cancer (5), colorectal cancer (6), and gastric adenocarcinoma (7). Alternate Names 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase; AMACR; AMACRD; CBAS4; P504S; RACE; RM Specification REACTIVITY: H M SENSITIVITY: Endogenous MW (kDa): 42 Source/Isotype: Mouse IgG2b