CST, 3350S, ApoA1 (5F4) Mouse Monoclonal Antibody

Monoclonal Antibody for studying APOA1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, ApoA1 (5F4) Mouse Monoclonal Antibody (CST #3350) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity ApoA1 (5F4) Mouse Monoclonal Antibody detects endogenous level of total ApoA1 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a full-length recombinant human ApoA1. Background ApoAI (Apolipoprotein A1) is a major component of high density lipoprotein (HDL, the "good cholesterol") in plasma. It is produced in the liver and small intestine. ApoA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) that is responsible for the formation of plasma cholesteryl esters and promotes cholesterol efflux from tissues to the liver for excretion. Defects in ApoA1 are associated with high density lipoprotein deficiency (HDLD) and systemic non-neuropathic amyloidosis (1-3). Alternate Names Apo-AI; apo(a); ApoA-I; APOA1; Apolipoprotein A-I; Apolipoprotein A-I(1-242); Apolipoprotein A1; epididymis secretory sperm binding protein; HPALP2; MGC117399; ProapoA-I; Proapolipoprotein A-I; Truncated apolipoprotein A-I Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 25 Source/Isotype: Mouse IgG1