CST, 33871T, SLC25A39 (F2F6O) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying SLC25A39. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, SLC25A39 (F2F6O) Rabbit Monoclonal Antibody (CST #33871) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity SLC25A39 (F2F6O) Rabbit Monoclonal Antibody recognizes endogenous levels of total SLC25A39 protein. A band of unknown origin is detected at ~90 kDa. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human SLC25A39 protein. Background Members of the solute carrier family 25 (SLC25) transport molecules across the inner mitochondrial membrane (1,2). Mutations in these carriers often result in rare but severe pathologies (3). Solute carrier family 25 member 39 (SLC25A39) and its paralogue SLC25A40 were found to be essential for mitochondrial import of glutathione, thereby protecting against oxidative stress and mitochondrial dysfunction (4,5). Changes in SLC25A39 and SLC25A40 expression were found in cholestasis-associated renal injury and LPS-induced inflammation (6). Alternate Names CGI-69; CGI69; FLJ22407; Probable mitochondrial glutathione transporter SLC25A39; S2539; SLC25A39; Solute carrier family 25 member 39; solute carrier family 25, member 39 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 36 Source/Isotype: Rabbit IgG