CST, 36468S, CHGA (5H7) Mouse Monoclonal Antibody

Monoclonal Antibody for studying CHGA. Validated for IHC Leica Bond,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, CHGA (5H7) Mouse Monoclonal Antibody (CST #36468) is ready to ship. Product Usage Information IHC Leica Bond: 1:100 - 1:400 Immunohistochemistry (Paraffin): 1:100 - 1:400 Storage Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 12 months when stored at 4°C. Do not aliquot the antibody. Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation. Protocol Available protocols: IHC Leica Bond, Immunohistochemistry (Paraffin) Specificity / Sensitivity CHGA (5H7) Mouse Monoclonal Antibody recognizes endogenous levels of CHGA protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to part of the central region of CHGA protein. Background Chromogranin A (CHGA) and Chromogranin B (CHGB) are members of the chromogranin/secretogranin family of neuroendocrine secretory proteins. They reside in the secretory vesicles of neurons and endocrine cells and are debated to regulate cargo in the secretory pathway (1,2).CHGA is also useful as a serological and immunohistological marker for the presence of neuroendocrine tumors (NETs) from various tissue sources (3,4). CHGA may also be useful for the assessment of disease progression (5,6). Alternate Names AL-11; betagranin (N-terminal fragment of chromogranin A); Catestatin; CgA; CHGA; chromofungin; chromogranin A; chromogranin A (parathyroid secretory protein 1); Chromogranin-A; CMGA; EA-92; ER-37; ES-43; GE-25; GR-44; GV-19; LF-19; p-Glu serpinin precursor; Pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14 Specification REACTIVITY: H SENSITIVITY: Endogenous Source/Isotype: Mouse IgG1