CST, 36734T, Kindlin-1 (D1K4C) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying kindlin-1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, Kindlin-1 (D1K4C) Rabbit Monoclonal Antibody (CST #36734) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity Kindlin-1 (D1K4C) Rabbit Monoclonal Antibody recognizes endogenous levels of total Kindlin-1 protein. This antibody does not cross-react with Kindlin-2 or Kindlin-3. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro159 of human Kindlin-1 protein. Background The kindlin family of focal adhesion proteins is involved in multiple biological processes, including integrin signaling, adhesion, migration, angiogenesis, differentiation, and mitotic spindle formation (1,2). Kindlin family members 1, 2, and 3 (FERM1, FERM2, and URP2) are differentially expressed in tissues. Kindlin-1 is primarily expressed in epithelial cells, kindlin-2 is ubiquitously expressed, and kindlin-3 expression is restricted to the hematopoietic system (3). Alternate Names C20orf42; DTGCU2; FERM1; Fermitin family homolog 1; fermitin family homolog 1 (Drosophila); fermitin family member 1; FERMT1; FLJ20116; FLJ23423; KIND1; Kindlerin; kindlin 1; Kindlin syndrome protein; Kindlin-1; Unc-112-related protein 1; UNC112 related protein 1; UNC112A; URP1 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 77 Source/Isotype: Rabbit IgG