CST, 37414S, CD1C (E6C9A) Mouse Monoclonal Antibody

Monoclonal Antibody for studying CD1C. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CD1C (E6C9A) Mouse Monoclonal Antibody (CST #37414) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity CD1C (E6C9A) Mouse Monoclonal Antibody recognizes endogenous levels of total CD1C protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with human CD1C recombinant protein. Background CD1C (T-cell surface glycoprotein CD1c) is a member of the CD1 family of major histocompatibility complex (MHC) class I-like proteins whose function is to present lipid-based antigens to T cells (1-5). CD1C is a single-pass type I membrane protein found on monocyte-derived dendritic cells, Langerhans cells, and a subset of B cells (1-5). CD1C is commonly used as a marker for myeloid dendritic cells (mDCs), which are the major population of dendritic cells in human blood, tissues, and lymphoid organs (3-5). Alternate Names BDCA1; CD1; CD1A; CD1C; CD1C antigen, c polypeptide; CD1c molecule; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; T-cell surface glycoprotein CD1c Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 40-50 Source/Isotype: Mouse IgG1 kappa