CST, 45723S, BHLHE40/DEC1 (E6T3E) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying BHLHB2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, BHLHE40/DEC1 (E6T3E) Rabbit Monoclonal Antibody (CST #45723) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:200 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity BHLHE40/DEC1 (E6T3E) Rabbit Monoclonal Antibody recognizes endogenous levels of total DEC1 protein. Species Reactivity: Human, Mouse Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human DEC1 protein. Background DEC1 (BHLHB2, BHLHE40) is a helix-loop-helix (bHLH) transcription factor that plays a role in the circadian system, or mammalian molecular clock (1-6). Its expression is elevated in response to various stimuli such as light pulses, growth factors, or hypoxia. DEC1 is involved in the homeostasis of regulatory T cells and the cellular differentiation, proliferation, and apoptosis of various cancers (4-6). Alternate Names basic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix family member e40; basic helix-loop-helix family, member e40; BHE40; BHLHB2; BHLHE40; Class B basic helix-loop-helix protein 2; Class E basic helix-loop-helix protein 40; Clast5; DEC1; differentially expressed in chondrocytes 1; Differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; Enhancer-of-split and hairy-related protein 2; FLJ99214; HLHB2; SHARP-2; SHARP2; Stimulated by retinoic acid gene 13 protein; STRA13; Stra14 Specification REACTIVITY: H M SENSITIVITY: Endogenous MW (kDa): 46 Source/Isotype: Rabbit IgG