CST, 47055T, CAP1 (D2K3J) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying CAP1. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CAP1 (D2K3J) Rabbit Monoclonal Antibody (CST #47055) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity CAP1 (D2K3J) Rabbit Monoclonal Antibody recognizes endogenous levels of total CAP1 protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val337 of human CAP1 protein. Background Adenylyl cyclase-associated protein 1 (CAP1) is a widely expressed actin regulatory protein that plays a role in adhesion through its interactions with talin1 and FAK (1). High CAP1 expression is associated with metastasis in hepatocellular carcinoma (2), and esophageal squamous cell carcinoma (3). Research studies also show that CAP1 expression in human epithelial ovarian cancer correlates with proliferation, histological grade, and prognosis (4). Alternate Names adenylate cyclase associated protein 1; Adenylyl cyclase-associated protein 1; CAP; CAP 1; CAP, adenylate cyclase-associated protein 1; CAP, adenylate cyclase-associated protein 1 (yeast); CAP1; CAP1-PEN; cyclase associated actin cytoskeleton regulatory protein 1; testis secretory sperm-binding protein Li 218p Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 56 Source/Isotype: Rabbit IgG