CST, 48913S, ARPC5 (F5F6V) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying ARPC5. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, ARPC5 (F5F6V) Rabbit Monoclonal Antibody (CST #48913) is ready to ship. Product Usage Information Western Blotting: 1:1000 Simple Western™: 1:10 - 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity ARPC5 (F5F6V) Rabbit Monoclonal Antibody recognizes endogenous levels of total ARPC5 protein. This antibody cross-reacts with ARPC5L protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to full-length human ARPC5 protein. Background Actin-related protein 2/3 complex subunit 5 (ARPC5) is a component of the ARP2/3 actin nucleation complex, which regulates actin dynamics and cellular processes such as cell migration, division, endocytosis, and vesicle trafficking (1). The ARP2/3 complex has also been shown to promote repair of DNA double-strand breaks through homologous recombination (2). ARPC5 expression is increased and associated with poor prognosis in several human cancers, including hepatocellular carcinoma, prostate cancer, gliomas, and multiple myeloma (3-6). Alternate Names actin related protein 2/3 complex subunit 5; actin related protein 2/3 complex, subunit 5, 16kDa; Actin-related protein 2/3 complex subunit 5; ARC16; Arp2/3 complex 16 kDa subunit; Arp2/3 protein complex subunit p16; ARPC5; dJ127C7.3; MGC88523; p16-ARC Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 16 Source/Isotype: Rabbit IgG