CST, 5557S, Succinyl-CoA Synthetase Antibody

Polyclonal Antibody for studying SUCLG1. Validated for Western Blotting,Immunoprecipitation. Highly specific and rigorously validated in-house, Succinyl-CoA Synthetase Antibody (CST #5557) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity Succinyl-CoA Synthetase Antibody detects endogenous levels of total succinyl-CoA synthetase (α subunit) protein. Species Reactivity: Human, Mouse, Rat Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human succinyl-CoA synthetase (α subunit) protein. Antibodies are purified by protein A and peptide affinity chromatography. Background Succinyl-CoA synthetase α subunit (SUCLG1) catalyzes the conversion of succinate to succinyl-CoA and plays a key role in the citric acid cycle (1,2). Deficiency of this enzyme leads to a variety of diseases including fatal infantile lactic acidosis (3) and mitochondrial hepatoencephalomyopathy (4). Alternate Names FLJ21114; FLJ43513; GALPHA; MTDPS9; SCS-alpha; SUCA; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase alpha subunit; succinate-CoA ligase GDP/ADP-forming subunit alpha; succinate-CoA ligase, alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SUCLA1; SUCLG1 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 36 SOURCE: Rabbit