CST, 62195S, MSR1 (E4H1C) Rabbit Monoclonal Antibody (Alexa Fluor® 647 Conjugate)

Monoclonal Antibody for studying MSR1 mouse. Validated for IF,IF,F,F. Highly specific and rigorously validated in-house, MSR1 (E4H1C) Rabbit Monoclonal Antibody (Alexa Fluor^® 647 Conjugate) (CST #62195) is ready to ship. Product Usage Information Immunofluorescence (Frozen): 1:50 Immunofluorescence (Immunocytochemistry): 1:400 - 1:1600 Flow Cytometry (Fixed/Permeabilized): 1:1600 Flow Cytometry (Live): 1:6400 Storage Supplied in PBS (pH 7.2), less than 0.1% sodium azide, and 2 mg/mL BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze. Protocol Available protocols: Immunofluorescence (Frozen), Immunofluorescence (Immunocytochemistry), Flow Cytometry (Fixed/Permeabilized), Flow Cytometry (Live) Specificity / Sensitivity MSR1 (E4H1C) Rabbit Monoclonal Antibody (Alexa Fluor Species Reactivity: Mouse Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of mouse MSR1 protein. Background Macrophage Scavenger receptor types I and II (MSR1, also known as SCARA1) are members of the class A macrophage scavenger receptor family. These proteins bind large quantities of modified lipoproteins and promote endocytosis. Upregulation of MSR1 in infiltrating myeloid cells may mediate clearance of specific damage signals in response to tissue injury, including ischemic stroke (1). MSR1 germline mutations are also associated with increased prostate cancer susceptibility in some patient cohorts (2). MSR1 is observed to be upregulated in differentiated THP-1 cells (3). Alternate Names CD204; Macrophage acetylated LDL receptor I and II; macrophage scavenger receptor 1; Macrophage scavenger receptor types I and II; MRS-A; MSR; MSR-A; Msr1; MSRE; Scara1; Scavenger receptor type A; Scvr; SR-A; SR-AI; SR-AII Specification REACTIVITY: M SENSITIVITY: Endogenous Source/Isotype: Rabbit IgG