CST, 68023S, PTPRCAP Antibody

Polyclonal Antibody for studying PTPRCAP. Validated for Western Blotting. Highly specific and rigorously validated in-house, PTPRCAP Antibody (CST #68023) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity PTPRCAP Antibody recognizes endogenous levels of total PTPRCAP protein. Species Reactivity: Human Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro140 of human PTPRCAP protein. Antibodies are purified by protein A and peptide affinity chromatography. Background Protein tyrosine phosphatase receptor type C-associated protein (PTPRCAP/LPAP) is a transmembrane adaptor protein in which expression is restricted to cells of the T- and B-lineages (1). Research studies have demonstrated that PTPRCAP undergoes tyrosine phosphorylation in response to T cell activation and is a positive regulator of T cell function (2-4). Alternate Names CD45 associated protein; CD45-AP; CD45-associated protein; LPAP; Lymphocyte phosphatase-associated phosphoprotein; MGC138602; MGC138603; protein tyrosine phosphatase receptor type C associated protein; Protein tyrosine phosphatase receptor type C-associated protein; protein tyrosine phosphatase, receptor type, c polypeptide-associated protein; protein tyrosine phosphatase, receptor type, C-associated protein; PTCA; PTPRC-associated protein; PTPRCAP Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 35 SOURCE: Rabbit