CST, 68030S, CA 19-9 (C241:5:1:4) Mouse Monoclonal Antibody

Monoclonal Antibody for studying . Validated for IHC Leica Bond,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, CA 19-9 (C241:5:1:4) Mouse Monoclonal Antibody (CST #68030) is ready to ship. Product Usage Information IHC Leica Bond: 1:400 - 1:1600 Immunohistochemistry (Paraffin): 1:800 - 1:3200 Storage Supplied in PBS containing 1% BSA and 15 mM sodium azide. Stable for 6 months when stored at 4°C. Do not aliquot the antibody. Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation. Protocol Available protocols: IHC Leica Bond, Immunohistochemistry (Paraffin) Specificity / Sensitivity CA 19-9 (C241:5:1:4) Mouse Monoclonal Antibody recognizes endogenous levels of CA 19-9 protein. This antibody has minimal cross-reactivity (<1%) with sialyl lacto-N-tetraosylceramide. This antibody does not cross-react with Lewis A, Lewis B, or structurally-related substances. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with human colorectal adenocarcinoma Colo 205 cells. Background CA 19-9 specifically binds to the epitope of sialylated Lewis A carbohydrate structure, which is the functional ligand for E-selectin and is involved in the adhesion of cancer cells (1,2). The CA 19-9 antigen has been of clinical interest in detection, diagnosis, and management of cancers such as pancreatic and gastrointestinal carcinomas (3,4). Specification REACTIVITY: H SENSITIVITY: Endogenous Source/Isotype: Mouse IgG1