CST, 71407S, Glut5 (F4A5K) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying GLUT5. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, Glut5 (F4A5K) Rabbit Monoclonal Antibody (CST #71407) is ready to ship. Product Usage Information Western Blotting: 1:1000 Simple Western™: 1:10 - 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity Glut5 (F4A5K) Rabbit Monoclonal Antibody recognizes endogenous levels of total Glut5 protein. This antibody does not cross-react with Glut1, Glut2, Glut3, or Glut4 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Glut5 protein. Background Glucose transporter 5 (Glut5, also known as SLC2A5) functions as a fructose transporter. Glut5 transports fructose into epithelial cells of small intestine (1,2). Besides the small intestine, Glut5 is also expressed in other tissues, such as skeletal muscle and the prostate gland (3). In addition, studies show that Glut5 expression is significantly upregulated in prostate cancer, and fructose promotes prostate cancer growth (2). Furthermore, fructose metabolism mediated by Glut5 in tumor endothelial cells from hepatocellular carcinoma (HCC) enhances tumor angiogenesis by boosting respiration in mitochondria (4). Alternate Names Fructose transporter; Glucose transporter type 5, small intestine; glucose transporter-like protein 5; GLUT-5; GLUT5; GTR5; SLC2A5; solute carrier family 2 (facilitated glucose transporter), member 5; solute carrier family 2 (facilitated glucose/fructose transporter), member 5; solute carrier family 2 member 5; Solute carrier family 2, facilitated glucose transporter member 5; testicular tissue protein Li 81 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 42-80 Source/Isotype: Rabbit IgG