CST, 72912S, RPL10 Antibody

Polyclonal Antibody for studying RPL10. Validated for Western Blotting. Highly specific and rigorously validated in-house, RPL10 Antibody (CST #72912) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity RPL10 Antibody recognizes endogenous levels of total RPL10 protein. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro205 of human RPL10 protein. Antibodies are purified by peptide affinity chromatography. Background Ribosomal protein L10 (RPL10), also known as QM, is an essential 60S ribosomal subunit protein that facilitates joining of the 40S and 60S subunits (1-3). During ribosome assembly, RPL10 is one of the last proteins to be added that make up the peptide transferase center, and is responsible for releasing nuclear export factor NMD3 (4,5). An R98S mutation in has been shown in T-cell acute lymphoblastic leukemia and additional mutations have been found in autism spectrum disorders (6-8). Alternate Names 60S ribosomal protein L10; AUTSX5; DKFZp686J1851; DXS648; DXS648E; FLJ23544; FLJ27072; L10; Laminin receptor homolog; Large ribosomal subunit protein uL16; MRXS35; NOV; Protein QM; QM; ribosomal protein L10; RL10; RPL10; Tumor suppressor QM; Wilms tumor-related protein Specification REACTIVITY: H M R Mk SENSITIVITY: Endogenous MW (kDa): 25 SOURCE: Rabbit