CST, 76163T, LAD1 (E3Q8E) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying LAD1. Validated for Western Blotting,Immunoprecipitation,Immunofluorescence (Immunocytochemistry). Available in 2 sizes. Highly specific and rigorously validated in-house, LAD1 (E3Q8E) Rabbit Monoclonal Antibody (CST #76163) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:100 Immunofluorescence (Immunocytochemistry): 1:100 - 1:400 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation, Immunofluorescence (Immunocytochemistry) Specificity / Sensitivity LAD1 (E3Q8E) Rabbit Monoclonal Antibody recognizes endogenous levels of total LAD1 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human LAD1 protein. Background LAD1/Ladinin-1 is a basement membrane anchoring protein associated with the basal surface of polarized cells, as well as with the actin cytoskeleton (1,2). LAD1 expression regulates migration and invasion of human cancer cells, and high expression of LAD1 is indicative of poor prognosis in several human cancers, including breast, colorectal, laryngeal, and prostate cancers (2-5). Â Alternate Names LAD; Lad-1; LAD1; LADA; ladinin 1; Ladinin-1; linear IgA bullous dermatosis antigen; Linear IgA disease antigen; linear IgA disease antigen homolog; MGC10355 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 65 Source/Isotype: Rabbit IgG