CST, 77593T, KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying KKLC1. Validated for Western Blotting,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody (CST #77593) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunohistochemistry (Paraffin): 1:50 - 1:200 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 29342 . Protocol Available protocols: Western Blotting, Immunohistochemistry (Paraffin) Specificity / Sensitivity KK-LC-1 (F3U6C) Rabbit Monoclonal Antibody recognizes endogenous levels of total KK-LC-1 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human KK-LC-1 protein. Background Kita-kyushu lung cancer antigen 1 (KK-LC-1), also known as CT83, is a small cancer-associated protein that was first discovered as a tumor-specific antigen in lung cancer (1). KK-LC-1 expression is restricted to the testis, but its aberrant expression has been observed in lung, gastric, liver, and triple-negative breast cancer (1-6). Although its exact biological function is not completely understood, KK-LC-1 is being targeted in multiple immunotherapies, including T cell receptor-engineered T cells (TCR-Ts) (7). Alternate Names Cancer/testis antigen 83; chromosome X open reading frame 61; CT83; CXorf61; FLJ20611; FLJ22913; Kita-kyushu lung cancer antigen 1; KK-LC-1; KKLC1 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 14 Source/Isotype: Rabbit IgG