CST, 77885T, IFI44L (E7A9V) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying IFI44L. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, IFI44L (E7A9V) Rabbit Monoclonal Antibody (CST #77885) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:200 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity IFI44L (E7A9V) Rabbit Monoclonal Antibody recognizes endogenous levels of total IFI44L protein. This antibody detects an 18 kDa band of unknown origin in some cell lines. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Phe85 of human IFI44L protein. Background IFI44L (interferon-induced protein 44-like) is a member of the IFI44 family of IFN-stimulated genes (ISG), which play a role in antiviral activity (1-5). IFI44L is induced by many viruses, including Respiratory Syncytial Virus (RSV) and Influenza A virus (IAV) (3,4). IFI44L may be involved in modulating innate immune responses to inflammation and inhibiting virus replication (1,3,4). IFI44L has been studied in relation to its antimicrobial activity and could be a potential prognostic marker for M. tuberculosis treatment (5). IFI44L may also play a suppressive role in Met/Src signaling in human hepatocellular carcinoma (2). Alternate Names C1orf29; GS3686; IF44L; IFI44L; interferon induced protein 44 like; Interferon-induced protein 44-like Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 47 Source/Isotype: Rabbit IgG