CST, 78247S, PPID (E7Y8I) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying PPID. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, PPID (E7Y8I) Rabbit Monoclonal Antibody (CST #78247) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:100 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity PPID (E7Y8I) Rabbit Monoclonal Antibody recognizes endogenous levels of total PPID protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human PPID protein. Background Peptidyl-prolyl cis-trans isomerase D (PPID) is a ubiquitously expressed cytoplasmic enzyme that catalyzes the cis-trans isomerization of proline imidic bonds within HSP90 complexes to facilitate folding of protein clients, such as steroid hormone receptors (1,2). Research studies have also demonstrated that PPID plays a role in regulating the assembly and release of viruses, such as HCV and SARS-CoV-2 (3,4). Alternate Names 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; CYP-40; CYP40; CYPD; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; PPIase D; PPID; Rotamase D; testicular tissue protein Li 147 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 42 Source/Isotype: Rabbit IgG