CST, 80158T, CCPG1 (E3C5G) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying CCPG1. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, CCPG1 (E3C5G) Rabbit Monoclonal Antibody (CST #80158) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity CCPG1 (E3C5G) Rabbit Monoclonal Antibody recognizes endogenous levels of total CCPG1 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human CCPG1 protein. Background CCPG1 (cell cycle progression protein 1) was originally identified as a scaffold protein for Rho- specific guanine nucleotide exchange specificity (1). More recently it has been shown to play an important role in ER homeostasis by functioning as a cargo receptor for ER selective autophagy, termed ER-phagy (2). CCPG1 is localized to the ER and is induced by stress (2, 3). It associates with components of autophagy including LC3 family members and the FIP200, a component of the ULK1 complex, facilitating the trafficking of the ER to the autophagosome (2). Alternate Names CCP8; CCPG1; cell cycle progression 1; cell cycle progression 8 protein; Cell cycle progression protein 1; Cell cycle progression restoration protein 8; CPR8; KIAA1254 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 105-120 Source/Isotype: Rabbit IgG