CST, 8071S, Succinyl-CoA Synthetase (D8A11) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying SUCLG1. Validated for WB,IP,IF,eCLIP. Available in 2 sizes. Highly specific and rigorously validated in-house, Succinyl-CoA Synthetase (D8A11) Rabbit Monoclonal Antibody (CST #8071) is ready to ship. Product Usage Information For more information about the RBP-eCLIP service please visit Eclipsebio . Western Blotting: 1:1000 Immunoprecipitation: 1:50 Immunofluorescence (Immunocytochemistry): 1:100 eCLIP: 1:200 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation, Immunofluorescence (Immunocytochemistry) Specificity / Sensitivity Succinyl-CoA Synthetase (D8A11) Rabbit Monoclonal Antibody detects endogenous levels of total succinyl-CoA synthetase (α subunit) protein. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human succinyl-CoA synthetase protein. Background Succinyl-CoA synthetase α subunit (SUCLG1) catalyzes the conversion of succinate to succinyl-CoA and plays a key role in the citric acid cycle (1,2). Deficiency of this enzyme leads to a variety of diseases including fatal infantile lactic acidosis (3) and mitochondrial hepatoencephalomyopathy (4). Alternate Names FLJ21114; FLJ43513; GALPHA; MTDPS9; SCS-alpha; SUCA; Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase alpha subunit; succinate-CoA ligase GDP/ADP-forming subunit alpha; succinate-CoA ligase, alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase subunit alpha; SUCLA1; SUCLG1 Specification REACTIVITY: H M R Mk SENSITIVITY: Endogenous MW (kDa): 36 Source/Isotype: Rabbit IgG