CST, 8104S, SignalSlide® Cleaved Caspase-3 (Asp175) IHC Controls

IHC Control Slides for studying Casp3 (Asp175) cleaved in the research area. Background Caspase-3 (CPP-32, Apopain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires the aspartic acid residue at the P1 position (2). Alternate Names active caspase 3; active caspase-3; Apopain; casp3; casp367; casp39; Caspase 3; Caspase-3; Caspase3; cleaved caspase 3; cleaved caspase-3; Control Slides; CPP 32; CPP-32; CPP32; IHC; SCA1; SignalSlideTM; Yama Protein