CST, 85345S, IFIT5 (E4O1Q) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying IFIT5. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, IFIT5 (E4O1Q) Rabbit Monoclonal Antibody (CST #85345) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:100 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity IFIT5 (E4O1Q) Rabbit Monoclonal Antibody recognizes endogenous levels of total IFIT5 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala340 of human IFIT5 protein. Background Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) is a member of the IFIT family of innate immune effector molecules that participate in defense against viral pathogens. Compared to other IFIT family members, the function of IFIT5 is the least understood. Research studies, however, have shown that IFIT5 contributes to the host innate immune antiviral response, in part, by binding to single-stranded viral RNAs (1,2). In addition, IFIT5 has been shown to enhance activation of NF-kB in response to viral infection (3,4). Alternate Names FLJ53857; FLJ92678; IFIT-5; IFIT5; interferon induced protein with tetratricopeptide repeats 5; Interferon-induced 58 kDa protein; Interferon-induced protein with tetratricopeptide repeats 5; ISG58; P58; Retinoic acid- and interferon-inducible 58 kDa protein; retinoic acid- and interferon-inducible protein (58kD); RI58 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 58 Source/Isotype: Rabbit IgG