CST, 87620T, ALKBH3 (E6S4R) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying ALKBH3. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, ALKBH3 (E6S4R) Rabbit Monoclonal Antibody (CST #87620) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity ALKBH3 (E6S4R) Rabbit Monoclonal Antibody recognizes endogenous levels of total ALKBH3 protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val10 of human ALKBH3 protein. Background ALKBH3, also known as Prostate Cancer Antigen-1 (PCA-1), is a DNA and RNA demethylase involved in the repair of alkylated DNA. The protein is overexpressed in prostate cancer and has been linked to other cancer types, including non-small cell lung cancer, renal cell carcinoma, and pancreatic carcinoma (1-3). ALKBH3/PCA-1 is also a potential therapeutic target in prostate cancer (4). Alternate Names ABH3; AlkB homolog 3; alkB homolog 3, alpha-ketoglutarate dependent dioxygenase; alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB, alkylation repair homolog 3; alkB, alkylation repair homolog 3 (E. coli); ALKB3; ALKBH3; Alkylated DNA repair protein alkB homolog 3; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3; DEPC-1; DEPC1; FLJ43614; hABH3; MGC118790; MGC118792; MGC118793; PCA1; Prostate cancer antigen 1; prostate cancer antigen-1 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 35 Source/Isotype: Rabbit IgG