CST, 8956S, Androgen Receptor (D6F11) Rabbit Monoclonal Antibody (Alexa Fluor® 555 Conjugate)

Monoclonal Antibody for studying Androgen Receptor. Validated for Immunofluorescence (Immunocytochemistry). Highly specific and rigorously validated in-house, Androgen Receptor (D6F11) Rabbit Monoclonal Antibody (Alexa Fluor^® 555 Conjugate) (CST #8956) is ready to ship. Product Usage Information Immunofluorescence (Immunocytochemistry): 1:80 - 1:160 Storage Supplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze. Protocol Available protocols: Immunofluorescence (Immunocytochemistry) Specificity / Sensitivity Androgen Receptor (D6F11) Rabbit Monoclonal Antibody (Alexa Fluor Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein corresponding to residues near the amino terminal region of human androgen receptor protein. Background Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3). Alternate Names AIS; ANDR; Androgen receptor; AR; AR8; DHTR; Dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; TFM Specification REACTIVITY: H SENSITIVITY: Endogenous Source/Isotype: Rabbit IgG