CST, 90916T, CD1A (MTB1) Mouse Monoclonal Antibody

Monoclonal Antibody for studying CD1A. Validated for IHC Leica Bond,Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, CD1A (MTB1) Mouse Monoclonal Antibody (CST #90916) is ready to ship. Product Usage Information IHC Leica Bond: 1:50 Immunohistochemistry (Paraffin): 1:50 Storage Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 6 months when stored at 4°C. Do not aliquot the antibody. Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation. Protocol Available protocols: IHC Leica Bond, Immunohistochemistry (Paraffin) Specificity / Sensitivity CD1A (MTB1) Mouse Monoclonal Antibody recognizes endogenous levels of CD1A protein. Non-specific staining was observed in testis by immunohistochemistry. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant fusion protein corresponding to the full external domain of human CD1A protein. Background CD1A is a type 1 cell surface transmembrane glycoprotein structurally similar to MHC Class 1 that is expressed in association with β2-microglobulin (1). CD1A is a member of the CD1 family and has been shown to mediate the presentation of primary lipid and glycolipid antigens to T cell lymphocytes for recognition (1,2). It is expressed by Langerhans' cells, cortical double positive and single positive thymocytes, and by interdigitating dendritic cells (1). CD1A has been shown to identify T cell development (3). Alternate Names CD1; CD1A; CD1A antigen, a polypeptide; CD1a molecule; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; HTA1; hTa1 thymocyte antigen; R4; T-cell surface antigen T6/Leu-6; T-cell surface glycoprotein CD1a; T6 Specification REACTIVITY: H SENSITIVITY: Endogenous Source/Isotype: Mouse IgG1 kappa