CST, 92185T, FABP3 (F1E1W) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying FABP3 mouse. Validated for Western Blotting,Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, FABP3 (F1E1W) Rabbit Monoclonal Antibody (CST #92185) is ready to ship. Product Usage Information Western Blotting: 1:1000 Simple Western™: 1:10 - 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity FABP3 (F1E1W) Rabbit Monoclonal Antibody recognizes endogenous levels of total FABP3 protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the amino terminus of mouse FABP3 protein. Background Fatty acid binding proteins (FABPs) are cytoplasmic lipid chaperones that bind fatty acids and lipids for transport to various cellular components (1,2). Research studies demonstrate differential FABP expression in various tumor types and their corresponding normal cell counterparts (3). Fatty acid binding protein 3 (FABP3) is predominantly expressed in heart, skeletal muscle, brain, and mammary gland (4). FABP3 may play a role in supplying energy to the heart and other tissues (5). FABP3 release from the heart upon infarction is used as a serum marker for myocardial stress and cardiotoxicity (6). Additional studies suggest that FABP3 is a potential tumor suppressor in breast cancer (7). It was also identified as a potential cerebrospinal fluid (CSF) biomarker for Alzheimer's disease (AD) and therapeutic target for Parkinson's disease (PD) (8,9). Alternate Names Fab; Fabp; Fabp3; FABPH; Fabph-1; Fabph-4; Fabph1; Fabph4; fatty acid binding protein 3, muscle and heart; fatty acid binding protein heart 1; fatty acid binding protein heart 4; Fatty acid-binding protein 3; Fatty acid-binding protein, heart; H-FA; H-FABP; Heart-type fatty acid-binding protein; Mammary-derived growth inhibitor; Mdg; MDGI; OTTMUSP00000009984 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 14 Source/Isotype: Rabbit IgG