CST, 93264S, CXCL14 (F1D8H) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying CXCL14. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, CXCL14 (F1D8H) Rabbit Monoclonal Antibody (CST #93264) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity CXCL14 (F1D8H) Rabbit Monoclonal Antibody recognizes endogenous levels of total CXCL14 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp50 of human CXCL14 protein. Background C-X-C motif chemokine ligand 14 (CXCL14) is a chemokine that acts as an attractant for a variety of immune cells, including neutrophils, dendritic cells, NK cells, and monocytes (1-4). Its receptor is unknown, though the mast cell receptor MRGPRX2 has been implicated as a candidate in a G protein-coupled receptor screen (5). is broadly expressed in normal tissues but is downregulated in various cancer types (6). Conversely, expression can be upregulated in lung cancer as well as other conditions, such as asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis, rheumatoid arthritis, psoriasis, and diabetes (5,7-11). Alternate Names BMAC; bolekine; BRAK; breast and kidney; C-X-C motif chemokine 14; C-X-C motif chemokine ligand 14; chemokine (C-X-C motif) ligand 14; Chemokine BRAK; CXC chemokine in breast and kidney; CXCL14; CXL14; KEC; KS1; MGC10687; MIP-2 gamma; MIP-2G; MIP2G; NJAC; SCYB14; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK); Small-inducible cytokine B14; tumor-suppressing chemokine Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 13 Source/Isotype: Rabbit IgG