CST, 95102T, Calretinin (CAL6) Mouse Monoclonal Antibody

Monoclonal Antibody for studying calretinin/CALB2. Validated for Immunohistochemistry (Paraffin). Available in 2 sizes. Highly specific and rigorously validated in-house, Calretinin (CAL6) Mouse Monoclonal Antibody (CST #95102) is ready to ship. Product Usage Information Immunohistochemistry (Paraffin): 1:50 Storage Supplied as liquid tissue culture supernatant containing sodium azide as a preservative. Stable for 12 months when stored at 4°C. Do not aliquot the antibody. Note: This product is only available in the format listed above. We are unable to provide this in a carrier free, custom formulation. Protocol Available protocols: Immunohistochemistry (Paraffin) Specificity / Sensitivity Calretinin (CAL6) Mouse Monoclonal Antibody recognizes endogenous levels of Calretinin protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a prokaryotic recombinant protein corresponding to the entire human Calretinin protein. Background Calretinin (29 kDa calbindin, calbindin 2) is a calcium-binding protein of the EF-hand family encoded by the gene. It is differentially expressed from homologous family member calbindin-d28k in distinct neuronal populations of the retina, auditory system, and cerebellar granule cells (1,2), and acts as a marker for specific neuronal subsets of the subthalamic nucleus and the substantia nigra (3). Calretinin has been shown to play an important role in modulating neuronal excitability and the induction of long-term potentiation (1). Research has shown that, pathologically, Calretinin is a selective marker for epithelial mesothelioma, making it a diagnostic tool to differentiate from adenocarcinomas (4). Alternate Names 29 kDa calbindin; CAB29; CAL2; CALB2; calbindin 2; calbindin 2, (29kD, calretinin); calbindin D29K; Calretinin; CR; testicular secretory protein Li 8 Specification REACTIVITY: H SENSITIVITY: Endogenous Source/Isotype: Mouse IgG2a