CST, 95214T, ENPP6 (E7P2Q) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying ENPP6 mouse. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, ENPP6 (E7P2Q) Rabbit Monoclonal Antibody (CST #95214) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity ENPP6 (E7P2Q) Rabbit Monoclonal Antibody recognizes endogenous levels of total ENPP6 protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro65 of mouse ENPP6 protein. Background Ectonucleotide pyrophosphatase/phosphodiesterase 6 (ENPP6) is a choline-specific glycerophosphodiesterase that belongs to the ENPP family. The seven ENPP family members play different biological roles in nucleotide and phospholipid signaling, bone mineralization, fibrotic diseases, and tumor-associated immune cell infiltration. ENPP6 is GPI-anchored to the plasma membrane and contains a PDE domain (1). This enzyme hydrolyzes polyunsaturated lysophosphatidylcholine (LPC), glycerophosphorylcholine (GPC), or sphingosylphosphorylcholine (SPC) in kidney and brain (2). It can be used as a marker of newly-forming oligodendrocytes in mouse brain (3). Alternate Names 4833421B01Rik; B830047L21Rik; Choline-specific glycerophosphodiester phosphodiesterase; D8Ertd514; D8Ertd514e; E-NPP 6; E-NPP6; ectonucleotide pyrophosphatase/phosphodiesterase 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6; Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 soluble form; Enpp6; Glycerophosphocholine cholinephosphodiesterase ENPP6; GPC-Cpde; NPP-6; Npp6 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 50 Source/Isotype: Rabbit IgG