CST, 95822T, WFDC2 (E8S8Z) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying WFDC2. Validated for Western Blotting. Available in 2 sizes. Highly specific and rigorously validated in-house, WFDC2 (E8S8Z) Rabbit Monoclonal Antibody (CST #95822) is ready to ship. Product Usage Information Western Blotting: 1:1000 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting Specificity / Sensitivity WFDC2 (E8S8Z) Rabbit Monoclonal Antibody recognizes endogenous levels of total WFDC2 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with recombinant protein specific to full-length human WFDC2 protein. This antibody recognizes residues surrounding Pro88 of human WFDC2 protein. Background WFDC2 (WAP four-disulfide core domain protein 2), also known as human epididymal secretory protein E4 (HE4), is a small secreted broad-range protease inhibitor. WFDC2 is a diagnostic marker in ovarian, endometrial and other cancers, and can be detected in patient serum (1,2). WFDC2 expression promotes tumor growth (3), contributes to metastasis and epithelial mesenchymal transition (EMT) (4), and regulates angiogenesis and immunogenic signaling in the tumor microenvironment (5). Alternate Names dJ461P17.6; EDDM4; epididymal protein 4; epididymal secretory protein E4; epididymis secretory sperm binding protein; epididymis-specific, whey-acidic protein type, four-disulfide core; HE4; major epididymis-specific protein E4; MGC57529; OTTHUMP00000031141; Putative protease inhibitor WAP5; Q14508; WAP domain containing protein HE4-V4; WAP four-disulfide core domain 2; WAP four-disulfide core domain protein 2; WAP5; WFDC2 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 20 Source/Isotype: Rabbit IgG