CST, 96510S, BASP1 (F9A5E) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying BASP1. Validated for Western Blotting,Immunohistochemistry (Paraffin),Immunofluorescence (Immunocytochemistry). Available in 2 sizes. Highly specific and rigorously validated in-house, BASP1 (F9A5E) Rabbit Monoclonal Antibody (CST #96510) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunohistochemistry (Paraffin): 1:1600 - 1:6400 Immunofluorescence (Immunocytochemistry): 1:1600 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunohistochemistry (Paraffin), Immunofluorescence (Immunocytochemistry) Specificity / Sensitivity BASP1 (F9A5E) Rabbit Monoclonal Antibody recognizes endogenous levels of total BASP1 protein. Non-specific staining was observed in cardiac and skeletal muscle by immunohistochemistry. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human BASP1 protein. Background Brain acid soluble protein 1 (BASP1) was originally isolated from brain extracts. It is abundant in nerve terminals during brain development and is implicated in neurite outgrowth, maturation of the actin cytoskeleton, organization of the plasma, and axon regeneration (1-3). Actin dynamics regulation and presynaptic vesicle cycling at axon terminals by BASP1 facilitate axon regeneration (2). Furthermore, the gene is downregulated in many human tumor cell lines, particularly in those derived from leukemias (4). Alternate Names 22 kDa neuronal tissue-enriched acidic protein; BASP1; brain abundant membrane attached signal protein 1; brain abundant, membrane attached signal protein 1; Brain acid soluble protein 1; brain acid-soluble protein 1; CAP-23; CAP23; MGC8555; NAP-22; NAP22; Neuronal axonal membrane protein NAP-22; neuronal tissue-enriched acidic protein Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 70 Source/Isotype: Rabbit IgG