CST, 96585T, DLX1 (E4T1L) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying DLX1. Validated for Western Blotting,Immunofluorescence (Frozen),Immunofluorescence (Immunocytochemistry). Available in 2 sizes. Highly specific and rigorously validated in-house, DLX1 (E4T1L) Rabbit Monoclonal Antibody (CST #96585) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunofluorescence (Frozen): 1:200 - 1:800 Immunofluorescence (Immunocytochemistry): 1:400 - 1:1600 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. For a carrier free (BSA and azide free) version of this product see product # 57480 . Protocol Available protocols: Western Blotting, Immunofluorescence (Frozen), Immunofluorescence (Immunocytochemistry) Specificity / Sensitivity DLX1 (E4T1L) Rabbit Monoclonal Antibody recognizes endogenous levels of total DLX1 protein. Species Reactivity: Human, Mouse, Rat Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His245 of human DLX1 protein. Background Homeobox protein DLX-1 (DLX1) is a member of a family of homeobox genes related to the distal-less gene. DLX1 is a transcription factor found in the forebrain of the developing mouse embryo, where it contributes to craniofacial development (1-3). DLX1 also plays a critical role in GABAergic neurogenesis and retinal development (4-7). The DNA-binding activity of DLX1 is mediated by its homeodomain, and DLX1 has been shown to bind to genes that promote neuronal migration and repress neurite growth (8,9). DLX1 expression is regulated by various non-coding RNAs in different cancer types (10-12). Alternate Names distal-less homeo box 1; distal-less homeobox 1; DLX1; Homeobox protein DLX-1 Specification REACTIVITY: H M R SENSITIVITY: Endogenous MW (kDa): 28 Source/Isotype: Rabbit IgG