CST, 97000T, UCP3 (D6J8K) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying UCP3. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, UCP3 (D6J8K) Rabbit Monoclonal Antibody (CST #97000) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity UCP3 (D6J8K) Rabbit Monoclonal Antibody recognizes endogenous levels of total UCP3 protein. This antibody does not cross-react with UCP1 or UCP2 proteins. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly110 of human UCP3 protein. Background Uncoupling protein 3 (UCP3), a mitochondrial inner membrane transport protein, is highly expressed in skeletal muscle and activates glucose transport in muscle cells (2). UCP3 lowers the production of reactive oxygen species in mitochondria by reducing the mitochondrial inner membrane potential (3). UCP3 has been implicated in the protection against fat-induced insulin resistance in skeletal muscle (4) and fat gain induced by high-fat feeding (1). Alternate Names Mitochondrial uncoupling protein 3; Putative mitochondrial transporter UCP3; SLC25A9; Solute carrier family 25 member 9; UCP 3; UCP3; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); Uncoupling protein-3 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 30 Source/Isotype: Rabbit IgG