CST, 97857S, RAI2 (D4W9P) Rabbit Monoclonal Antibody

Monoclonal Antibody for studying RAI2. Validated for Western Blotting,Immunoprecipitation. Available in 2 sizes. Highly specific and rigorously validated in-house, RAI2 (D4W9P) Rabbit Monoclonal Antibody (CST #97857) is ready to ship. Product Usage Information Western Blotting: 1:1000 Immunoprecipitation: 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at -20°C. Do not aliquot the antibody. Protocol Available protocols: Western Blotting, Immunoprecipitation Specificity / Sensitivity RAI2 (D4W9P) Rabbit Monoclonal Antibody recognizes endogenous levels of total RAI2 protein. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg522 of human RAI2 protein. Background Retinoic acid-induced protein 2 (RAI2) is a 530 amino acid protein, encoded by the gene on XP22.3 (1). RAI2 contains a central, proline-rich domain that is hypothesized to play a role in protein-protein interactions, and is expressed in a variety of embryonic and adult tissues (2). Beyond that, little is known about the biological functions of RAI2. Notably, a 2015 research study reported that suppressing RAI2 led to increased hematogenous dissemination of breast cancer cells to bone marrow, suggesting that RAI2 may function to negatively regulate tumor metastasis (3). Alternate Names OTTHUMP00000022997; OTTHUMP00000022998; Q9Y5P3; RAI2; retinoic acid induced 2; Retinoic acid-induced protein 2; retinoic acid-induced protein 2 isoform 1 Specification REACTIVITY: H SENSITIVITY: Endogenous MW (kDa): 78 Source/Isotype: Rabbit IgG