BRAND / VENDOR: Merck

Merck, 52332-25GMCN, Phenylmethylsulfonyl Fluoride

CATALOG NUMBER: 52332-25GMCN

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Product Description

Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. Effective at a concentration of 50 µM.

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