New England Biolabs, T3017L, Monarch® Spin Columns S2C and Tubes

Spin columns containing a proprietary silica matrix for nucleic acid binding. They are available for purchase separately for your convenience and supplied with Monarch Spin Collection Tubes ( Related Categories High Molecular Weight DNA Extraction,, Genomic DNA Extraction & Purification,, Nucleic Acid Purification Applications Nucleic Acid Purification FAQ Q: I notice that I'm applying force to fit the column into a collection tube. Should I be doing this? What collection tubes are compatible with columns? A: Matching collection tubes are provided in all Monarch® kits for the spin columns. If you use collection tubes outside of a given kit, please use the Monarch® Spin Collection Tubes (NEB #T2118). Do not force any columns into non-recommended collection tubes that have a very tight fit to avoid damaging the column. Q: I noticed that the Monarch Spin Columns S2C (NEB #T3017) are now tinted orange. Does this impact performance? A: The Monarch Spin Columns S2C are now tinted orange. The tinted color does not impact performance. Follow the recommended usage guidelines, including maximum input guidelines in the manual. Store the tinted columns protected from light to avoid fading of the tint over time. There may be natural variations in the tinting across the columns. Q: I see some silica residue in my Monarch column. Is this a problem? A: No, this is not an issue. The presence of some silica residue or particles in the nucleic acid purification column does not impact nucleic acid binding or purity. Our columns are designed to retain silica fibers, helping ensure they do not end up in the final eluate.