Product Description
Size: 20ul / 150ul
The BRSK2 (11589-1-AP) by Proteintech is a Polyclonal antibody targeting BRSK2 in WB, ELISA applications with reactivity to human, mouse, rat samples
11589-1-AP targets BRSK2 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse brain tissue, mouse testis tissue, rat brain tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:8000
Background Information
BRSK2 is highly conserved from invertebrates to human, plays a key role in polarization of neurons and has been identified with different names: SAD1 is its closest homolog in C. elegans, serine/threonine kinase SADA alfa in rat, brain-selective kinase 2 and SAD-B in mouse and hsSAD1 and SAD1B in humans(PMID:16165222) . In rat and mouse, BRSK2 is only detected in the brain and at low levels in the testis .It has some isoforms produced by alternative splicing with the molecular mass of 68-84 kDa. This protein has a conserved function throughout the evolution.
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag2195 Product name: Recombinant human BRSK2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-170 aa of BC024291 Sequence: MSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATGGPAVFQKPVKFQVDITYTEGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDPPAAQHLSEPPPPAPGLSWGAGLKGQKVATSYESSL Predict reactive species
Full Name: BR serine/threonine kinase 2
Calculated Molecular Weight: 87 kDa
Observed Molecular Weight: 80-88 kDa
GenBank Accession Number: BC024291
Gene Symbol: BRSK2
Gene ID (NCBI): 9024
RRID: AB_2243660
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q8IWQ3
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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