Proteintech, 11786-1-AP, CCL11/Eotaxin Polyclonal antibody

Size: 20ul / 150ul The CCL11/Eotaxin (11786-1-AP) by Proteintech is a Polyclonal antibody targeting CCL11/Eotaxin in IHC, ELISA applications with reactivity to human samples 11786-1-AP targets CCL11/Eotaxin in IHC, ELISA applications and shows reactivity with human samples. Tested Applications Positive IHC detected in: human lung squamous cell carcinoma tissue, human tonsillitis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Immunohistochemistry (IHC): IHC : 1:800-1:3200 Background Information CCL11 also named Eotaxin-1, was initially discovered as an eosinophil-specific chemoattractant. CCL11 plays a central role in both allergic and non-allergic inflammatory reactions by recruiting immune cells such as eosinophils,basophils and Th2 lymphocytes. CCL11 binds to the chemokine receptors CCR2, CCR3 and CCR5, with highest affinity to CCR3. High levels of CCL11 have been described in several chronic inflammatory diseases, such as allergic rhinitis, atopic dermatitis, asthma, gastrointestinal disease and rheumatoid arthritis. Specification Tested Reactivity: human Cited Reactivity: mouse, rat Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag2398 Product name: Recombinant human Eotaxin protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-97 aa of BC017850 Sequence: MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP Predict reactive species Full Name: chemokine (C-C motif) ligand 11 Calculated Molecular Weight: 97 aa, 11 kDa GenBank Accession Number: BC017850 Gene Symbol: CCL11/Eotaxin Gene ID (NCBI): 6356 RRID: AB_10860099 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P51671 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.