Product Description
Size: 20ul / 150ul
The MCM10 (12251-1-AP) by Proteintech is a Polyclonal antibody targeting MCM10 in WB, ELISA applications with reactivity to human, mouse samples
12251-1-AP targets MCM10 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HEK-293 cells, HeLa cells, K-562 cells, Ramos cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
MCM10, also named as HsMCM10, belongs to the MCM10 family. It acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, it plays a role in preventing DNA damage during replication and is essential for the integrity of the RECQ4-MCM replicative helicase complex. It mediates RECQ4 association with MCM2-7 helicase complex during DNA replication.
Specification
Tested Reactivity: human, mouse
Cited Reactivity: human, mouse, chicken
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag2899 Product name: Recombinant human MCM10 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 259-611 aa of BC009108 Sequence: MDLPTCGARNLKQHLAKASASGIMGSPKPAIKSISASALLKQQKQRMLEMRRRKSEEIQKRFLQSSSEVESPAVPSSSRQPPAQPPRTGSEFPRLEGAPATMTPKLGRGVLEGDDVLFYDESPPPRPKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERVEKNTMFSSQAEDELEPARKKRREQLAYLESEEFQKILKAKSKHTGILKEAEAEMQERYFEPLVKKEQMEEKMRNIREVKCRVVTCKTCAYTHFKLLETCVSEQHEYHWHDGVKRFFKCPCGNRSISLDRLPNKHCSNCGLYKWERDGMLKEKTGPKIGGETLLPRGEEHAKFLNSLK Predict reactive species
Full Name: minichromosome maintenance complex component 10
Calculated Molecular Weight: 874 aa, 97 kDa
Observed Molecular Weight: 97-105 kDa
GenBank Accession Number: BC009108
Gene Symbol: MCM10
Gene ID (NCBI): 55388
RRID: AB_2266259
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q7L590
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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