Product Description
Size: 20ul / 150ul
The GADD45A (13747-1-AP) by Proteintech is a Polyclonal antibody targeting GADD45A in WB, ELISA applications with reactivity to human samples
13747-1-AP targets GADD45A in WB, IHC, IF, CoIP, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HEK-293 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
GADD45A, also named as DDIT1 and GADD45, belongs to the GADD45 family. It binds to proliferating cell nuclear antigen. GADD45A may affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. GADD45A plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cells. GADD45A has Dimer (~28-36 kDa) and Monomer (14-18 kDa) forms (PMID:11498536).
Specification
Tested Reactivity: human
Cited Reactivity: human, mouse, rat, goat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag4687 Product name: Recombinant human GADD45A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 5-165 aa of BC011757 Sequence: EFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAKLLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGPAASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPER Predict reactive species
Full Name: growth arrest and DNA-damage-inducible, alpha
Calculated Molecular Weight: 165 aa, 18 kDa
Observed Molecular Weight: 18 kDa, 33 kDa
GenBank Accession Number: BC011757
Gene Symbol: GADD45A
Gene ID (NCBI): 1647
RRID: AB_2108058
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P24522
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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