Proteintech, 14321-1-AP, HOXC4 Polyclonal antibody

Size: 20ul / 150ul The HOXC4 (14321-1-AP) by Proteintech is a Polyclonal antibody targeting HOXC4 in WB, ELISA applications with reactivity to human, rat samples 14321-1-AP targets HOXC4 in WB, ELISA applications and shows reactivity with human, rat samples. Tested Applications Positive WB detected in: Jurkat cells, PC-12 cells, U-251 cells Recommended dilution Western Blot (WB): WB : 1:5000-1:50000 Background Information The class I homeobox (HOX) family of homeodomain-containing transcription factors has 39 members in mammals. These genes are distributed throughout the genome in four clusters: HOXA (7p15), HOXB (17q21), HOXC (12q13), and HOXD (2q31). HOX genes are known to act as transcription factors, playing an essential regulatory role in the temporal and spatial development of the embryo. HOXC family members are not expressed in normal prostate tissue but increased expression of HOXC genes is commonly detected in prostate cancers. HOXC4 is expressed in GC B cells and HoxC4 expression is specifically up-regulated by the same stimuli that induce AID expression (LPS, CD154 and IL-4). The calculated molecular weight of HOXC4 is 30 kDa. Sometimes higher molecular weight around 39 kDa can also be observed, which may be a modified variant of HOXC4 (PMID: 23178148, 32012197, 35400027). Specification Tested Reactivity: human, rat Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag5563 Product name: Recombinant human HOXC4 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-264 aa of BC050442 Sequence: MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPSYNGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRSAPPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL Predict reactive species Full Name: homeobox C4 Calculated Molecular Weight: 30 kDa Observed Molecular Weight: 39 kDa GenBank Accession Number: BC050442 Gene Symbol: HOXC4 Gene ID (NCBI): 3221 RRID: AB_2233196 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P09017 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.