Proteintech, 14746-1-AP, CLP1 Polyclonal antibody

Size: 20ul / 150ul The CLP1 (14746-1-AP) by Proteintech is a Polyclonal antibody targeting CLP1 in WB, ELISA applications with reactivity to human, mouse samples 14746-1-AP targets CLP1 in WB, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse testis tissue, HeLa cells Recommended dilution Western Blot (WB): WB : 1:500-1:1000 Background Information CLP1, also named as HEAB, is a 425 amino acid protein, which belongs to the Clp1 family. CLP1 as a polynucleotide kinase, that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. Human CLP1 is a component of the mRNA 3'end cleavage and polyadenylation machinery4,5 and studies in yeast have postulated a function for CLP1 in coupling mRNA 3' end processing with RNA Pol II transcriptional termination. CLP1 exists 2 isoforms with MV 41 kDa and 48 kDa. Specification Tested Reactivity: human, mouse Cited Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag6479 Product name: Recombinant human CLP1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 123-425 aa of BC000446 Sequence: TDVGKSTVCRLLLNYAVRLGRRPTYVELDVGQGSVSIPGTMGALYIERPADVEEGFSIQAPLVYHFGSTTPGTNIKLYNKITSRLADVFNQRCEVNRRASVSGCVINTCGWVKGSGYQALVHAASAFEVDVVVVLDQERLYNELKRDLPHFVRTVLLPKSGGVVERSKDFRRECRDERIREYFYGFRGCFYPHAFNVKFSDVKIYKVGAPTIPDSCLPLGMSQEDNQLKLVPVTPGRDMVHHLLSVSTAEGTEENLSETSVAGFIVVTSVDLEHQVFTVLSPAPRPLPKNFLLIMDIRFMDLK Predict reactive species Full Name: CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae) Calculated Molecular Weight: 48 kDa Observed Molecular Weight: 41 kDa, 48 kDa GenBank Accession Number: BC000446 Gene Symbol: CLP1 Gene ID (NCBI): 10978 RRID: AB_2878076 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q92989 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.