Product Description
Size: 20ul / 150ul
The INSL3 (17997-1-AP) by Proteintech is a Polyclonal antibody targeting INSL3 in WB, ELISA applications with reactivity to human, mouse, rat samples
17997-1-AP targets INSL3 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: human testis tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
Insulin-like 3 (INSL3), a Leydig cell-specific hormone, is essential for testis descent during foetal life and bone metabolism in adults. Insl3-deficient mice exhibit bilateral undescended testes located high in the abdominal cavity. INSL3 is presumed also to conform to a heterodimeric A-B structure of approximately 6 kDa once released from the producing cells. It is possible that both the mature form of INSL3 (6.6 kDa) and the pro-form(s) of INSL3 (12-14 kDa) are secreted from mammalian Leydig cells (PMID: 19329805).
Specification
Tested Reactivity: human, mouse, rat
Cited Reactivity: rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag12455 Product name: Recombinant human INSL3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 17-131 aa of BC071706 Sequence: LVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPAAGGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLLTLCPY Predict reactive species
Full Name: insulin-like 3 (Leydig cell)
Calculated Molecular Weight: 131 aa, 14 kDa
Observed Molecular Weight: 18 kDa
GenBank Accession Number: BC071706
Gene Symbol: INSL3
Gene ID (NCBI): 3640
RRID: AB_2878479
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P51460
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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