Product Description
Size: 20ul / 150ul
The Collagen Type VII (19799-1-AP) by Proteintech is a Polyclonal antibody targeting Collagen Type VII in WB, ELISA applications with reactivity to human samples
19799-1-AP targets Collagen Type VII in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
COL7A1, also named as LC collagen, is a stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica (DEB). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Pasini type (P-DEB) which also known as albopapuloid dominant dystrophic epidermolysis bullosa. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Hallopeau-Siemens type (HS-DEB). Defects in COL7A1 are the cause of transient bullous dermolysis of the newborn (TBDN). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica pretibial type (PR-DEB). Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica Bart type (B-DEB). Defects in COL7A1 are the cause of epidermolysis bullosa pruriginosa (EBP). Defects in COL7A1 are the cause of isolated toenail dystrophy without skin fragility. Defects in COL7A1 are the cause of epidermolysis bullosa dystrophica with subcorneal cleavage (EBDSC) which also known as epidermolysis bullosa simplex superficialis (EBSS). This antibody is specific to COL7A1.
Specification
Tested Reactivity: human
Cited Reactivity: human, mouse
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: Peptide Predict reactive species
Full Name: collagen, type VII, alpha 1
Calculated Molecular Weight: 295 kDa
Observed Molecular Weight: 290 kDa
GenBank Accession Number: NM_000094
Gene Symbol: COL7A1
Gene ID (NCBI): 1294
RRID: AB_2878609
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: Q02388
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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