Proteintech, 20043-1-AP, LPHN2 Polyclonal antibody

Size: 20ul / 150ul The LPHN2 (20043-1-AP) by Proteintech is a Polyclonal antibody targeting LPHN2 in IHC, IF-P, ELISA applications with reactivity to human, mouse samples 20043-1-AP targets LPHN2 in IHC, IF-P, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive IHC detected in: mouse cerebellum tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Positive IF-P detected in: mouse cerebellum tissue Recommended dilution Immunohistochemistry (IHC): IHC : 1:50-1:500 Immunofluorescence (IF)-P: IF-P : 1:50-1:500 Background Information LPHN2, Latrophilin-2, is a calcium-independent receptor of low affinity for alpha-latrotoxin which triggers massive exocytosis from neurons and neuroendocrine cells. LPHN2 is a novel receptor of LRG1 that rescues vascular and neurological abnormalities (PMID: 35562586). LPHN2 and LPHN3 serve as postsynaptic recognition molecules in CA1 pyramidal neurons of the hippocampus, localized to Purkinje cells in cerebellum (PMID: 32202499). Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Peptide Predict reactive species Full Name: latrophilin 2 Calculated Molecular Weight: 163 kDa GenBank Accession Number: NM_012302 Gene Symbol: LPHN2 Gene ID (NCBI): 23266 RRID: AB_3085596 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: O95490 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.