Proteintech, 21007-1-AP, Thyroid Hormone Receptor beta Polyclonal antibody

Size: 20ul / 150ul The Thyroid Hormone Receptor beta (21007-1-AP) by Proteintech is a Polyclonal antibody targeting Thyroid Hormone Receptor beta in WB, ELISA applications with reactivity to Mouse samples 21007-1-AP targets Thyroid Hormone Receptor beta in WB, IHC, IF, ELISA applications and shows reactivity with Mouse samples. Tested Applications Positive WB detected in: mouse retina tissue, mouse eye tissue Recommended dilution Western Blot (WB): WB : 1:1000-1:6000 Background Information Thyroid hormone receptor beta (THRB), also known as ERBA2, NR1A2, and THR1, belongs to the nuclear hormone receptor family and NR1 subfamily. THRB is a nuclear hormone receptor that can act as a repressor or activator of transcription. Moreover, THRB is also a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. THRB is the most abundant THR isoform in the liver but is also expressed in other tissues and mediates the effects of THs on hepatic carbohydrate and lipid metabolism (PMID: 34884910). Specification Tested Reactivity: Mouse Cited Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag15210 Product name: Recombinant human THRB protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 112-461 aa of BC106929 Sequence: DKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED Predict reactive species Full Name: thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) Calculated Molecular Weight: 476 aa, 54 kDa Observed Molecular Weight: 50 kDa GenBank Accession Number: BC106929 Gene Symbol: Thyroid Hormone Receptor beta Gene ID (NCBI): 7068 RRID: AB_3085632 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: P10828 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.