Product Description
Size: 20ul / 150ul
The ITIH1 (21141-1-AP) by Proteintech is a Polyclonal antibody targeting ITIH1 in WB, ELISA applications with reactivity to human, mouse, rat samples
21141-1-AP targets ITIH1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse auricular cartilage tissue, mouse cartilage tissue, rat auricular cartilage tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
ITIH1 (inter-alpha-trypsin inhibitor heavy chain 1), also named as IGHEP1 and SHAP. It is a key component of the inter-alpha-trypsin inhibitor (ITI) family, which plays a crucial role in extracellular matrix (ECM) stabilization and inflammation regulation. ITIH1 forms a complex with bikunin (a light chain) and other heavy chains (ITIH2, ITIH3, ITIH4), contributing to the stabilization of hyaluronan-rich matrices. The calculated molecular weight of the ITIH1 mature form is 101 kDa, but the actual observed molecular weight is about 76 kDa (PMID: 9677337).
Specification
Tested Reactivity: human, mouse, rat
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Immunogen: CatNo: Ag15598 Product name: Recombinant human ITIH1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 608-811 aa of BC069464 Sequence: SMSIRGMADQDGLKPTIDKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQD Predict reactive species
Full Name: inter-alpha (globulin) inhibitor H1
Calculated Molecular Weight: 911 aa, 101 kDa
Observed Molecular Weight: 70-76 kDa
GenBank Accession Number: BC069464
Gene Symbol: ITIH1
Gene ID (NCBI): 3697
Conjugate: Unconjugated
Form: Liquid
Purification Method: Antigen affinity purification
UNIPROT ID: P19827
Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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