Proteintech, 22860-1-AP, ADAM33 Polyclonal antibody

Size: 20ul / 150ul The ADAM33 (22860-1-AP) by Proteintech is a Polyclonal antibody targeting ADAM33 in WB, ELISA applications with reactivity to human samples 22860-1-AP targets ADAM33 in WB, ELISA applications and shows reactivity with human samples. Tested Applications Positive WB detected in: MCF-7 cells, SK-BR-3 cells Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Background Information ADAM33 is a member of the 'a disintegrin and metalloprotease domain' family of proteins. Endogenous ADAM33 is detected in bronchus tissue, bronchial smooth muscle cells, and MRC-5 fibroblasts, consistent with a role in the pathophysiology of asthma(PMID:12535637). ADAM33 is a novel tumour suppressor gene that may be useful as a molecular marker for invasive lobular carcinoma of the breast(PMID:19267929) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag18852 Product name: Recombinant human ADAM33 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 30-364 aa of BC125113 Sequence: VLQGHIPGQPVTPHWVLDGQPWRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNHTDHCHYQGRVRGFPDSWVVLCTCSGMSGLITLSRNASYYLRPWPPRGSKDFSTHEIFRMEQLLTWKGTCGHRDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRNLNHTKQRLLEVANYVDQLLRTLDIQVALTGLEVWTERDRSRRQLRAFFRKGGGACLSNAPDPGLPVPPALCGNGFVEAGEECDCGPGQECRDLCCFAHNCSLRPGAQCAHGDCCVRCLLKPAGALCRQAMGDCDL Predict reactive species Full Name: ADAM metallopeptidase domain 33 Calculated Molecular Weight: 813 aa, 88 kDa Observed Molecular Weight: 70 kDa GenBank Accession Number: BC125113 Gene Symbol: ADAM33 Gene ID (NCBI): 80332 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9BZ11 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.