Proteintech, 24603-1-AP, UPB1 Polyclonal antibody

Size: 20ul / 150ul The UPB1 (24603-1-AP) by Proteintech is a Polyclonal antibody targeting UPB1 in WB, IHC, ELISA applications with reactivity to human, mouse samples 24603-1-AP targets UPB1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples. Tested Applications Positive WB detected in: mouse liver tissue Positive IHC detected in: human heart tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0 Recommended dilution Western Blot (WB): WB : 1:500-1:2000 Immunohistochemistry (IHC): IHC : 1:20-1:200 Background Information BUP1(Beta-ureidopropionase) is also named as BUP1, Beta-alanine synthase, N-carbamoyl-beta-alanine amidohydrolase and belongs to the CN hydrolase family. It catalyzes the last step in the pyrimidine degradation pathway that it converts N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to, respectively, beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide. It is a protein with a calculated molecular mass of 43 kDa. It can also exist in the form of homodimer, homotetramer, homooctamer, and higher homooligomers. (PMID: 29976570) Specification Tested Reactivity: human, mouse Host / Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: CatNo: Ag18960 Product name: Recombinant human UPB1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-384 aa of BC131703 Sequence: MAGAEWKSLEECLEKHLPLPDLQEVKRVLYGKELRKLDLPREAFEAASREDFELQGYAFEAAEEQLRRPRIVHVGLVQNRIPLPANAPVAEQVSALHRRIKAIVEVAAMCGVNIICFQEAWTMPFAFCTREKLPWTEFAESAEDGPTTRFCQKLAKNHDMVVVSPILERDSEHGDVLWNTAVVISNSGAVLGKTRKNHIPRVGDFNESTYYMEGNLGHPVFQTQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCFTCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE Predict reactive species Full Name: ureidopropionase, beta Calculated Molecular Weight: 384 aa, 43 kDa Observed Molecular Weight: 43 kDa, 80 kDa GenBank Accession Number: BC131703 Gene Symbol: UPB1 Gene ID (NCBI): 51733 RRID: AB_2879634 Conjugate: Unconjugated Form: Liquid Purification Method: Antigen affinity purification UNIPROT ID: Q9UBR1 Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.